Physical Activity and Redox Balance in the Elderly: Signal Transduction Mechanisms

Reactive Oxygen Species (ROS) are molecules naturally produced by cells. If their levels too high, the cellular antioxidant machinery intervenes to bring back quantity physiological conditions. Since aging often induces malfunctioning in this machinery, ROS considered an effective cause of age-associated diseases. Exercise stimulates production on one side, and systems other side. The effects exercise oxidative stress markers have been shown blood, vascular tissue, brain, cardiac skeletal muscle, both young aged people. However, intensity volume individual subject characteristics important envisage future strategies adequately personalize balance oxidant/antioxidant environment. Here, we reviewed literature that deals with physical activity redox people, insights into molecular mechanisms involved. Although many pathways involved, still far from a comprehensive view stand behind during aging. believe precision medicine will be able transform administration wellness targeted prevention, as yet admit topic is its infancy.